Spyre Therapeutics, Inc. SEC filings SYRE
Spyre Therapeutics, Inc. has 823 filings in SEC EDGAR's recent list, going back to Mar 24, 2015. Its latest annual report, Form ARS, was filed on Apr 10, 2026 for the period ended Dec 31, 2025. The latest quarterly report (Form 10-Q) was filed on Nov 3, 2026, covering the quarter ended Sep 30, 2026. The most recent current report (Form 8-K) was filed on Nov 3, 2026 (results of operations). The company's fiscal year ends on December 31.
| Form | Description | Filed | Period |
|---|---|---|---|
| 8-K |
Current report
Results of operations
|
Nov 3, 2026 | Nov 3, 2026 |
| 10-Q | Quarterly report | Nov 3, 2026 | Sep 30, 2026 |
| 8-K |
Current report
Material agreement
|
Oct 7, 2026 | Oct 5, 2026 |
| 424B5 | Prospectus supplement | Oct 6, 2026 | — |
| 424B5 | Prospectus supplement | Oct 5, 2026 | — |
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Sep 8, 2026 | Sep 8, 2026 |
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Aug 25, 2026 | Aug 25, 2026 |
| 8-K |
Current report
Results of operations
|
Aug 4, 2026 | Aug 4, 2026 |
| 10-Q | Quarterly report | Aug 4, 2026 | Jun 30, 2026 |
| S-3ASR | Automatic shelf registration | Jun 26, 2026 | — |
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Jun 15, 2026 | Jun 15, 2026 |
| 8-K |
Current report
Other events
|
Jun 1, 2026 | May 29, 2026 |
| 8-K |
Current report
Officer or director change, Shareholder vote results
|
May 29, 2026 | May 27, 2026 |
| 8-K |
Current report
Results of operations
|
May 5, 2026 | May 5, 2026 |
| 10-Q | Quarterly report | May 5, 2026 | Mar 31, 2026 |
| 8-K |
Current report
Material agreement
|
Apr 16, 2026 | Apr 14, 2026 |
| 424B5 | Prospectus supplement | Apr 16, 2026 | — |
| 424B5 | Prospectus supplement | Apr 13, 2026 | — |
| 8-K |
Current report
Results of operations, Other events
|
Apr 13, 2026 | Apr 13, 2026 |
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Apr 13, 2026 | Apr 13, 2026 |
| ARS | Annual report to shareholders | Apr 10, 2026 | Dec 31, 2025 |
| DEFA14A | Additional proxy material | Apr 10, 2026 | — |
| DEF 14A | Proxy statement | Apr 10, 2026 | May 27, 2026 |
| EFFECT | Filing | Mar 4, 2026 | — |
| EFFECT | Filing | Feb 27, 2026 | — |
| POS AM | Filing | Feb 27, 2026 | — |
| CORRESP | Letter to the SEC | Feb 25, 2026 | — |
| UPLOAD | Letter from the SEC | Feb 25, 2026 | — |
| S-3 | Shelf registration | Feb 19, 2026 | — |
| S-8 | Employee stock plan registration | Feb 19, 2026 | — |
| 8-K |
Current report
Results of operations
|
Feb 19, 2026 | Feb 19, 2026 |
| 10-K | Annual report | Feb 19, 2026 | Dec 31, 2025 |
| 8-K |
Current report
Regulation FD disclosure
|
Jan 12, 2026 | Jan 12, 2026 |
| 8-K |
Current report
Results of operations, Regulation FD disclosure, Other events
|
Nov 4, 2025 | Nov 4, 2025 |
| 10-Q | Quarterly report | Nov 4, 2025 | Sep 30, 2025 |
| 8-K |
Current report
Material agreement
|
Oct 15, 2025 | Oct 13, 2025 |
| 424B5 | Prospectus supplement | Oct 14, 2025 | — |
| 424B5 | Prospectus supplement | Oct 14, 2025 | — |
| 8-K |
Current report
Results of operations
|
Oct 14, 2025 | Oct 14, 2025 |
| S-8 | Employee stock plan registration | Aug 5, 2025 | — |
| 8-K |
Current report
Results of operations
|
Aug 5, 2025 | Aug 5, 2025 |
| 10-Q | Quarterly report | Aug 5, 2025 | Jun 30, 2025 |
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Jun 17, 2025 | Jun 17, 2025 |
| 8-K |
Current report
Shareholder vote results
|
Jun 2, 2025 | May 29, 2025 |
| UPLOAD | Letter from the SEC | Jun 2, 2025 | — |
| CORRESP | Letter to the SEC | May 21, 2025 | — |
| UPLOAD | Letter from the SEC | May 9, 2025 | — |
| 8-K |
Current report
Results of operations
|
May 8, 2025 | May 8, 2025 |
| 10-Q | Quarterly report | May 8, 2025 | Mar 31, 2025 |
| ARS | Annual report to shareholders | Apr 14, 2025 | Dec 31, 2024 |
| DEFA14A | Additional proxy material | Apr 14, 2025 | — |
| DEF 14A | Proxy statement | Apr 14, 2025 | May 29, 2025 |
| EFFECT | Filing | Mar 13, 2025 | — |
| EFFECT | Filing | Mar 7, 2025 | — |
| POS AM | Filing | Mar 7, 2025 | — |
| 8-K |
Current report
Auditor change
|
Mar 6, 2025 | Feb 28, 2025 |
| CORRESP | Letter to the SEC | Mar 5, 2025 | — |
| UPLOAD | Letter from the SEC | Mar 4, 2025 | — |
| S-3 | Shelf registration | Feb 27, 2025 | — |
| S-8 | Employee stock plan registration | Feb 27, 2025 | — |
| 8-K |
Current report
Results of operations
|
Feb 27, 2025 | Feb 27, 2025 |
| 10-K | Annual report | Feb 27, 2025 | Dec 31, 2024 |
| 8-K |
Current report
Results of operations, Other events
|
Jan 13, 2025 | Jan 13, 2025 |
| 8-K |
Current report
Material agreement
|
Nov 19, 2024 | Nov 18, 2024 |
| 424B5 | Prospectus supplement | Nov 19, 2024 | — |
| 424B5 | Prospectus supplement | Nov 18, 2024 | — |
| 10-Q/A | Amended quarterly report | Nov 18, 2024 | Sep 30, 2024 |
| 10-Q/A | Amended quarterly report | Nov 18, 2024 | Jun 30, 2024 |
| 10-Q/A | Amended quarterly report | Nov 18, 2024 | Mar 31, 2024 |
| 10-K/A | Amended annual report | Nov 18, 2024 | Dec 31, 2023 |
| 8-K |
Current report
Restatement, Other events
|
Nov 18, 2024 | Nov 18, 2024 |
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Nov 12, 2024 | Nov 12, 2024 |
| S-8 | Employee stock plan registration | Nov 7, 2024 | — |
| 8-K |
Current report
Results of operations
|
Nov 7, 2024 | Nov 7, 2024 |
| 10-Q | Quarterly report | Nov 7, 2024 | Sep 30, 2024 |
| 8-K |
Current report
Material agreement, Regulation FD disclosure, Other events
|
Oct 15, 2024 | Oct 11, 2024 |
| EFFECT | Filing | Oct 2, 2024 | — |
| CORRESP | Letter to the SEC | Sep 30, 2024 | — |
| UPLOAD | Letter from the SEC | Sep 26, 2024 | — |
| S-3 | Shelf registration | Sep 20, 2024 | — |
| EFFECT | Filing | Sep 18, 2024 | — |
| CORRESP | Letter to the SEC | Sep 13, 2024 | — |
| UPLOAD | Letter from the SEC | Sep 12, 2024 | — |
| S-3 | Shelf registration | Sep 6, 2024 | — |
| 424B3 | Prospectus | Aug 8, 2024 | — |
| 8-K/A |
Amended current report
Other events
|
Aug 8, 2024 | Aug 7, 2024 |
| 8-K |
Current report
Results of operations
|
Aug 7, 2024 | Aug 7, 2024 |
| 10-Q | Quarterly report | Aug 7, 2024 | Jun 30, 2024 |
| 8-K |
Current report
Regulation FD disclosure
|
May 30, 2024 | May 30, 2024 |
| 424B3 | Prospectus | May 15, 2024 | — |
| 8-K |
Current report
Material agreement, Officer or director change, Bylaw or fiscal year change, Shareholder vote results, Regulation FD disclosure
|
May 15, 2024 | May 13, 2024 |
| 8-K |
Current report
Results of operations
|
May 9, 2024 | May 9, 2024 |
| 10-Q | Quarterly report | May 9, 2024 | Mar 31, 2024 |
| EFFECT | Filing | Apr 29, 2024 | — |
| CORRESP | Letter to the SEC | Apr 25, 2024 | — |
| 8-K |
Current report
Unregistered share sale
|
Apr 25, 2024 | Apr 23, 2024 |
| UPLOAD | Letter from the SEC | Apr 25, 2024 | — |
| S-1 | Registration statement | Apr 19, 2024 | — |
| ARS | Annual report to shareholders | Apr 2, 2024 | Dec 31, 2023 |
| SEC STAFF LETTER | Filing | Apr 2, 2024 | — |
| EFFECT | Filing | Apr 1, 2024 | — |
| EFFECT | Filing | Apr 1, 2024 | — |
| DEF 14A | Proxy statement | Apr 1, 2024 | May 13, 2024 |
| CORRESP | Letter to the SEC | Mar 28, 2024 | — |
| POS AM | Filing | Mar 27, 2024 | — |
| S-1/A | Amended registration statement | Mar 27, 2024 | — |
| CORRESP | Letter to the SEC | Mar 26, 2024 | — |
| PRE 14A | Preliminary proxy statement | Mar 20, 2024 | May 13, 2024 |
| 424B3 | Prospectus | Mar 18, 2024 | — |
| 8-K |
Current report
Material agreement, Unregistered share sale, Bylaw or fiscal year change, Regulation FD disclosure
|
Mar 18, 2024 | Mar 18, 2024 |
| CORRESP | Letter to the SEC | Mar 14, 2024 | — |
| POS AM | Filing | Mar 14, 2024 | — |
| S-1/A | Amended registration statement | Mar 14, 2024 | — |
| UPLOAD | Letter from the SEC | Mar 8, 2024 | — |
| POS AM | Filing | Mar 5, 2024 | — |
| CORRESP | Letter to the SEC | Mar 1, 2024 | — |
| S-1/A | Amended registration statement | Mar 1, 2024 | — |
| 10-K/A | Amended annual report | Mar 1, 2024 | Dec 31, 2023 |
| S-8 | Employee stock plan registration | Feb 29, 2024 | — |
| 8-K |
Current report
Results of operations
|
Feb 29, 2024 | Feb 29, 2024 |
| 10-K | Annual report | Feb 29, 2024 | Dec 31, 2023 |
| UPLOAD | Letter from the SEC | Feb 16, 2024 | — |
| 424B3 | Prospectus | Feb 7, 2024 | — |
| 8-K |
Current report
Material agreement, Officer or director change, Bylaw or fiscal year change
|
Feb 5, 2024 | Feb 1, 2024 |
| S-1/A | Amended registration statement | Feb 5, 2024 | — |
| CORRESP | Letter to the SEC | Feb 2, 2024 | — |
| SEC STAFF LETTER | Filing | Jan 19, 2024 | — |
| UPLOAD | Letter from the SEC | Jan 18, 2024 | — |
| 8-K |
Current report
Listing notice
|
Jan 18, 2024 | Jan 16, 2024 |
| D | Filing | Dec 27, 2023 | — |
| S-8 | Employee stock plan registration | Dec 22, 2023 | — |
| S-1 | Registration statement | Dec 22, 2023 | — |
| 424B3 | Prospectus | Dec 8, 2023 | — |
| 8-K |
Current report
Material agreement, Unregistered share sale, Bylaw or fiscal year change, Regulation FD disclosure
|
Dec 8, 2023 | Dec 7, 2023 |
| 424B3 | Prospectus | Nov 30, 2023 | — |
| 8-K |
Current report
Officer or director change, Bylaw or fiscal year change, Regulation FD disclosure
|
Nov 28, 2023 | Nov 22, 2023 |
| 8-K |
Current report
Bylaw or fiscal year change, Shareholder vote results, Regulation FD disclosure
|
Nov 24, 2023 | Nov 21, 2023 |
| EFFECT | Filing | Nov 20, 2023 | — |
| CORRESP | Letter to the SEC | Nov 17, 2023 | — |
| CORRESP | Letter to the SEC | Nov 15, 2023 | — |
| S-1/A | Amended registration statement | Nov 15, 2023 | — |
| 8-K |
Current report
Other events
|
Nov 15, 2023 | Nov 15, 2023 |
| 10-Q | Quarterly report | Nov 9, 2023 | Sep 30, 2023 |
| 8-K |
Current report
Results of operations
|
Nov 9, 2023 | Nov 9, 2023 |
| DEF 14A | Proxy statement | Oct 27, 2023 | Nov 21, 2023 |
| CORRESP | Letter to the SEC | Oct 26, 2023 | — |
| UPLOAD | Letter from the SEC | Oct 24, 2023 | — |
| 8-K |
Current report
Regulation FD disclosure
|
Oct 24, 2023 | Oct 24, 2023 |
| UPLOAD | Letter from the SEC | Oct 20, 2023 | — |
| S-1/A | Amended registration statement | Oct 10, 2023 | — |
| PRER14A | Filing | Oct 10, 2023 | — |
| 8-K |
Current report
Officer or director change, Other events
|
Oct 10, 2023 | Jun 22, 2023 |
| CORRESP | Letter to the SEC | Oct 6, 2023 | — |
| CORRESP | Letter to the SEC | Oct 6, 2023 | — |
| 8-K |
Current report
Material agreement
|
Oct 5, 2023 | Sep 29, 2023 |
| UPLOAD | Letter from the SEC | Sep 29, 2023 | — |
| 8-K |
Current report
Material agreement, Listing notice, Officer or director change
|
Sep 25, 2023 | Sep 19, 2023 |
| CORRESP | Letter to the SEC | Sep 8, 2023 | — |
| 8-K |
Current report
Change to shareholder rights, Bylaw or fiscal year change, Regulation FD disclosure, Other events
|
Sep 8, 2023 | Sep 7, 2023 |
| 8-K |
Current report
Officer or director change, Other events
|
Sep 5, 2023 | Aug 31, 2023 |
| UPLOAD | Letter from the SEC | Aug 28, 2023 | — |
| 10-Q | Quarterly report | Aug 11, 2023 | Jun 30, 2023 |
| 8-K |
Current report
Results of operations
|
Aug 11, 2023 | Aug 11, 2023 |
| 8-K |
Current report
Agreement ended
|
Aug 11, 2023 | Aug 7, 2023 |
| PRE 14A | Preliminary proxy statement | Aug 8, 2023 | Aug 7, 2023 |
| S-3 | Shelf registration | Aug 7, 2023 | — |
| 8-K |
Current report
Material agreement, Agreement ended, Acquisition or sale of assets, Regulation FD disclosure, Other events
|
Jul 27, 2023 | Jul 27, 2023 |
| 8-K |
Current report
Listing notice
|
Jul 14, 2023 | Jul 13, 2023 |
| D | Filing | Jul 6, 2023 | — |
| 8-K |
Current report
Material agreement, Acquisition or sale of assets, Unregistered share sale, Officer or director change, Bylaw or fiscal year change, Regulation FD disclosure
|
Jun 23, 2023 | Jun 21, 2023 |
| 8-K |
Current report
Other events
|
Jun 22, 2023 | Jun 22, 2023 |
| 8-K |
Current report
Shareholder vote results
|
Jun 9, 2023 | Jun 6, 2023 |
| DEFA14A | Additional proxy material | May 19, 2023 | — |
| 8-K |
Current report
Officer or director change
|
May 19, 2023 | May 15, 2023 |
| 10-Q | Quarterly report | May 11, 2023 | Mar 31, 2023 |
| 8-K |
Current report
Results of operations
|
May 11, 2023 | May 11, 2023 |
| 8-K |
Current report
Results of operations, Regulation FD disclosure
|
Apr 25, 2023 | Apr 25, 2023 |
| ARS | Annual report to shareholders | Apr 17, 2023 | Dec 31, 2022 |
| DEF 14A | Proxy statement | Apr 17, 2023 | Jun 6, 2023 |
| 8-K |
Current report
Exit or restructuring costs, Officer or director change, Other events
|
Apr 12, 2023 | Apr 8, 2023 |
| PRE 14A | Preliminary proxy statement | Apr 7, 2023 | Jun 6, 2023 |
| 8-K |
Current report
Other events
|
Mar 13, 2023 | Mar 10, 2023 |
| S-8 | Employee stock plan registration | Mar 2, 2023 | — |
| 424B5 | Prospectus supplement | Mar 2, 2023 | — |
| 10-K | Annual report | Mar 2, 2023 | Dec 31, 2022 |
| 8-K |
Current report
Results of operations, Regulation FD disclosure
|
Mar 2, 2023 | Mar 2, 2023 |
| 8-K |
Current report
Listing notice
|
Jan 18, 2023 | Jan 13, 2023 |
| 8-K |
Current report
Regulation FD disclosure
|
Jan 9, 2023 | Jan 9, 2023 |
| 8-K |
Current report
Officer or director change
|
Jan 6, 2023 | Jan 5, 2023 |
| 8-K |
Current report
Bylaw or fiscal year change
|
Dec 19, 2022 | Dec 15, 2022 |
| 8-K |
Current report
Officer or director change
|
Nov 30, 2022 | Nov 28, 2022 |
| 8-K |
Current report
Other events
|
Nov 15, 2022 | Nov 15, 2022 |
| 10-Q | Quarterly report | Nov 3, 2022 | Sep 30, 2022 |
| 8-K |
Current report
Results of operations, Regulation FD disclosure
|
Nov 3, 2022 | Nov 3, 2022 |
| 8-K |
Current report
Other events
|
Oct 4, 2022 | Oct 4, 2022 |
| 8-K |
Current report
Regulation FD disclosure
|
Sep 6, 2022 | Sep 6, 2022 |
| 8-K |
Current report
Officer or director change, Other events
|
Aug 25, 2022 | Aug 23, 2022 |
| 8-K |
Current report
Other events
|
Aug 18, 2022 | Aug 18, 2022 |
| 10-Q | Quarterly report | Aug 4, 2022 | Jun 30, 2022 |
| 8-K |
Current report
Results of operations, Regulation FD disclosure
|
Aug 4, 2022 | Aug 4, 2022 |
Showing 200 filings, the most recent 200. Main filings leave out insider and ownership forms such as Form 4; choose a type above to see them. Each form opens on SEC.gov. Older filings are on SEC EDGAR.
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Company profile
- Industry
- Pharmaceutical Preparations (SIC 2834)
- Listed as
- SYRE (Nasdaq)
- Fiscal year ends
- December 31
- Incorporated in
- DE
- Headquarters
- Waltham, MA
- SEC filer status
- Large accelerated filer
- SEC CIK
- 1636282
- Former names
- Aeglea BioTherapeutics, Inc. (until Nov 24, 2023)
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Source: SEC EDGAR filings. This is company-reported data, not investment advice.