Spyre Therapeutics, Inc. SYRE

Q4 FY2024 · ended Dec 31, 2024 · Revenue $0 · Filed Feb 19, 2026

Spyre Therapeutics, Inc. (SYRE) files with the SEC under industry code 2834, Pharmaceutical Preparations.

Revenue
$0
Net income
$-96.12M
-759.5% vs year-ago quarter
Operating cash flow
$-77.50M
-108.8% vs year-ago quarter
Free cash flow
—
EPS
$-0.74
Dividend per share
None
Shares outstanding
94.97M
+22.4% vs year-ago quarter
Net cash
—
Operating margin
—

Company profile

Industry
Pharmaceutical Preparations (SIC 2834)
Listed as
SYRE (Nasdaq)
Fiscal year ends
December 31
Incorporated in
DE
Headquarters
Waltham, MA
SEC filer status
Large accelerated filer
SEC CIK
1636282
Former names
Aeglea BioTherapeutics, Inc. (until Nov 24, 2023)

Other Pharmaceutical Preparations companies

Key figures

Fiscal-year totals from the annual reports; switch to Annual for the full-year view. Balance sheet lines are as of each year end.

Line
Q3 FY2026
Sep 30, 2026
Q2 FY2026
Jun 30, 2026
Q1 FY2026
Mar 31, 2026
Q4 FY2025
Dec 31, 2025
Q3 FY2025
Sep 30, 2025
Operating income
-$105.7M
-$41.6M
-$45.6M
-$57.2M
-$56.9M
Net income
-$96.1M
-$36.2M
-$69.0M
-$62.5M
-$11.2M
Diluted EPS
—
—
-$0.74
—
—
Operating cash flow
-$77.5M
-$69.9M
-$57.4M
-$44.6M
-$37.1M
Total assets
$1.1B
$1.2B
$764.0M
$777.8M
$504.6M
Total liabilities
$48.2M
$71.9M
$93.1M
$62.5M
$49.5M
Stockholders' equity
$1.1B
$1.1B
$670.8M
$715.2M
$455.1M
Cash and investments
$1.1B
$1.1B
$741.5M
$756.5M
$486.2M

Recent SEC filings

Recent SEC filings
Form Description Filed Period
8-K Current report
Results of operations
Nov 3, 2026 Nov 3, 2026
10-Q Quarterly report Nov 3, 2026 Sep 30, 2026
8-K Current report
Material agreement
Oct 7, 2026 Oct 5, 2026
8-K Current report
Regulation FD disclosure, Other events
Sep 8, 2026 Sep 8, 2026
8-K Current report
Regulation FD disclosure, Other events
Aug 25, 2026 Aug 25, 2026
8-K Current report
Results of operations
Aug 4, 2026 Aug 4, 2026

Source: SEC EDGAR filings. This is company-reported data, not investment advice.