Septerna, Inc. balance sheet SEPN

Annual Quarterly

As of Jun 30, 2026, Septerna, Inc. had total assets of $566.7 million and total liabilities of $180.0 million. Total assets were up 36.5% from a year earlier. Stockholders' equity was $386.7 million. It held $516.5 million in cash and investments against $22.5 million of total debt, net cash of $494.0 million. The current ratio, current assets divided by current liabilities, was 4.99.

USD in millions, except ratios and per-share amounts. The percent under a figure is the change from the same quarter a year earlier.

Line	Q2 FY2026 Jun 30, 2026	Q1 FY2026 Mar 31, 2026	Q4 FY2025 Dec 31, 2025	Q3 FY2025 Sep 30, 2025	Q2 FY2025 Jun 30, 2025	Q1 FY2025 Mar 31, 2025	Q4 FY2024 Dec 31, 2024	Q3 FY2024 Sep 30, 2024
Assets
Cash	85 -55.3%	72 -65.9%	121 -49.3%	320 +262.6%	189	210	238	88
Short-term investments	288 +109.6%	276 +119.0%	270 +139.8%	154 +265.0%	137	126	113	42
Long-term investments	144 +174.0%	175 +180.7%	158 +125.5%	87 +1149.6%	53	62	70	7
Cash and investments	517 +36.2%	522 +31.1%	549 +30.4%	562 +308.4%	379	398	421	138
Receivables	12 +7953.0%	11 +4236.8%	10 +5956.1%	9 +4016.7%	0	0	0	0
Total current assets	396 +18.6%	368 +7.5%	411 +15.2%	492 +268.5%	334	342	357	133
Property and equipment, net	4 -16.8%	4 -14.2%	4 -12.9%	4 -20.3%	5	5	5	5
Total assets	567 +36.5%	570 +31.3%	596 +30.6%	607 +248.1%	415	434	457	174
Liabilities and equity
Accounts payable	4 -39.3%	7 +71.6%	10 +221.3%	4 -39.1%	7	4	3	6
Total current liabilities	79 +424.3%	78 +634.8%	87 +576.6%	75 +469.0%	15	11	13	13
Total liabilities	180 +377.8%	191 +466.5%	214 +486.9%	218 +480.6%	38	34	37	38
Stockholders' equity	387 +2.4%	378 -5.4%	382 -9.1%	389 +544.7%	378	400	420	-87
Debt
Lease liabilities	23 -8.2%	23 -7.7%	24 -7.3%	24 -4.4%	25	25	25	25
Total debt	23 -8.2%	23 -7.7%	24 -7.3%	24 -4.4%	25	25	25	25
Net cash	494 +39.3%	499 +33.7%	525 +32.8%	537 +378.6%	355	373	395	112
Ratios
Current ratio	4.99x	4.71x	4.73x	6.53x	22.09x	32.19x	27.77x	10.08x
Debt to equity	0.06x	0.06x	0.06x	0.06x	0.07x	0.06x	0.06x	—
Return on equity	-6.27%	-9.52%	-12.80%	-15.13%	—	—	-17.09%	—
Return on assets	-4.28%	-6.33%	-8.20%	-9.69%	—	—	-15.73%	—
Book value per share	8.47	8.43	8.52	8.71	8.47	9.01	9.46	—

How these figures are calculated

Quarterly columns are single-quarter amounts. When a 10-Q reports only a year-to-date total, as cash flow statements do, the quarter is that total minus the previous quarter's year-to-date total. The fourth quarter is the annual report's full year minus the first nine months. A column marked YTD is a year-to-date total, shown when the earlier report needed for the single quarter is missing. USD in millions, except ratios and per-share amounts. Cash and investments adds short-term and long-term marketable securities to cash. Debt due within a year is the borrowings that are not already in long-term debt. Total debt is those borrowings plus lease liabilities. Net cash is cash and investments minus total debt. Return on equity and return on assets divide the trailing twelve months of net income by the balance on that date. Debt to EBITDA uses the trailing twelve months of EBITDA. More on our methodology.

Company profile

Industry: Pharmaceutical Preparations (SIC 2834)
Listed as: SEPN (Nasdaq)
Fiscal year ends: December 31
Incorporated in: DE
Headquarters: South San Francisco, CA
SEC filer status: , Emerging growth company
SEC CIK: 1984086

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Source: SEC EDGAR filings. This is company-reported data, not investment advice.