Vertex Pharmaceuticals Inc / Ma revenue by segment VRTX

Annual Quarterly

Vertex Pharmaceuticals Inc / Ma splits its revenue into 7 lines in its filings. The largest line in Q3 of fiscal 2026, the quarter ended Sep 30, 2026 was TRIKAFTAKAFTRIO at $2.4 billion, 71% of the total.

USD in millions. The percent under a figure is the change from the same quarter a year earlier.

Line	TTM Sep 30, 2026	Q3 FY2026 Sep 30, 2026	Q2 FY2026 Jun 30, 2026	Q1 FY2026 Mar 31, 2026	Q4 FY2025 Dec 31, 2025	Q3 FY2025 Sep 30, 2025	Q2 FY2025 Jun 30, 2025	Q1 FY2025 Mar 31, 2025	Q4 FY2024 Dec 31, 2024
Revenue	12,952	3,441	3,334	2,987	3,190	3,076	2,965	2,770	2,912
TRIKAFTAKAFTRIO	—	2,437 -8.2% share 70.8%	2,497 -2.1% share 74.9%	2,355 -7.1% share 78.8%	2,572 -5.5% share 80.6%	2,654 share 86.3%	2,551 share 86.0%	2,536 share 91.5%	2,721 share 93.4%
ALYFTREK	—	706 +185.7% share 20.5%	574 +265.8% share 17.2%	424 +687.4% share 14.2%	380 share 11.9%	247 share 8.0%	157 share 5.3%	54 share 1.9%	—
Manufactured Product Other	—	130 -6.3% share 3.8%	137 -29.2% share 4.1%	136 -12.5% share 4.5%	237 +24.2% share 7.4%	139 share 4.5%	194 share 6.5%	155 share 5.6%	191 share 6.6%
CASGEVY	—	99 +487.0% share 2.9%	76 +151.3% share 2.3%	43 +202.1% share 1.4%	54 share 1.7%	17 share 0.5%	30 share 1.0%	14 share 0.5%	—
JOURNAVX	—	58 +197.4% share 1.7%	50 +313.3% share 1.5%	29 +2130.8% share 1.0%	27 share 0.8%	20 share 0.6%	12 share 0.4%	1 share 0.0%	—
PALSONIFY	—	10 share 0.3%	—	—	—	—	—	—	—
Collaborativeand Royalty	—	—	—	—	0 share 0.0%	—	21 share 0.7%	10 share 0.4%	—

How these figures are calculated

Quarterly columns are single-quarter amounts. When a 10-Q reports only a year-to-date total, as cash flow statements do, the quarter is that total minus the previous quarter's year-to-date total. The fourth quarter is the annual report's full year minus the first nine months. A column marked YTD is a year-to-date total, shown when the earlier report needed for the single quarter is missing. USD in millions. Each group is a separate split of total revenue, so the groups are not added together. Share of revenue is that line divided by total revenue. The first column adds the latest year-to-date segment amount to the last fiscal year and subtracts the year-ago year-to-date amount. More on our methodology.

Company profile

Industry: Pharmaceutical Preparations (SIC 2834)
Listed as: VRTX (Nasdaq)
Fiscal year ends: December 31
Incorporated in: MA
Headquarters: Boston, MA
SEC filer status: Large accelerated filer
SEC CIK: 875320

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Source: SEC EDGAR filings. This is company-reported data, not investment advice.