Q2 FY2026 · ended Jun 30, 2026 · Revenue $773,000, -17.5% YoY · Filed Aug 11, 2026
Upstream Bio, Inc. (UPB) files with the SEC under industry code 2834, Pharmaceutical Preparations. In Q2 of fiscal 2026, the quarter ended Jun 30, 2026, it reported revenue of $773,000 and a net loss of $39.7 million. Free cash flow was -$35.6 million. As of Jun 30, 2026 it held $261.3 million in cash and investments and $954,000 in total debt.
Revenue
$773,000
-17.5% vs year-ago quarter
Net income
$-39.70M
+0.7% vs year-ago quarter
Operating cash flow
$-35.62M
+9.2% vs year-ago quarter
Free cash flow
$-35.62M
+9.3% vs year-ago quarter
EPS
$-0.73
+1.4% vs year-ago quarter
Dividend per share
None
Shares outstanding
54.77M
+1.6% vs year-ago quarter
Net cash
$260.35M
Q2 FY2026
Operating margin
-5382.6%
TTM
Company profile
- Industry
- Pharmaceutical Preparations (SIC 2834)
- Listed as
- UPB (Nasdaq)
- Fiscal year ends
- December 31
- Incorporated in
- DE
- Headquarters
- Waltham, MA
- SEC filer status
- , Emerging growth company
- SEC CIK
- 2022626
Other Pharmaceutical Preparations companies
- ELI LILLY & Co LLY
- Johnson & Johnson JNJ
- AbbVie Inc. ABBV
- Merck & Co., Inc. MRK
- Novartis AG NVS
- Astrazeneca PLC AZN
- Abbott Laboratories ABT
- Novo Nordisk A S NVO
Key figures
Fiscal-year totals from the annual reports; switch to Annual for the full-year view. Balance sheet lines are as of each year end.
| Line | Q2 FY2026 Jun 30, 2026 |
Q1 FY2026 Mar 31, 2026 |
Q4 FY2025 Dec 31, 2025 |
Q3 FY2025 Sep 30, 2025 |
Q2 FY2025 Jun 30, 2025 |
|---|---|---|---|---|---|
| Revenue | $773,000 | $1.0M | $668,000 | $683,000 | $937,000 |
| Operating income | -$42.4M | -$43.6M | -$46.2M | -$37.8M | -$44.3M |
| Net income | -$39.7M | -$40.6M | -$42.5M | -$33.7M | -$40.0M |
| Diluted EPS | -$0.73 | -$0.75 | -$0.79 | -$0.63 | -$0.74 |
| Operating cash flow | -$35.6M | -$47.9M | -$30.6M | -$22.2M | -$39.2M |
| Free cash flow | -$35.6M | — | -$30.7M | -$22.3M | -$39.3M |
| Total assets | $281.2M | $318.1M | $353.8M | $391.2M | $420.5M |
| Total liabilities | $10.2M | $14.1M | $14.0M | $12.6M | $11.8M |
| Stockholders' equity | $271.0M | $304.0M | $339.8M | $378.6M | $408.7M |
| Cash and investments | $261.3M | $294.6M | $341.5M | $372.4M | $393.6M |
| Total debt | $954,000 | $1.1M | $1.3M | $1.4M | $1.6M |
Recent SEC filings
| Form | Description | Filed | Period |
|---|---|---|---|
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Sep 1, 2026 | Sep 1, 2026 |
| 10-Q | Quarterly report | Aug 11, 2026 | Jun 30, 2026 |
| 8-K |
Current report
Results of operations
|
Aug 11, 2026 | Aug 11, 2026 |
| 8-K |
Current report
Shareholder vote results
|
Jun 10, 2026 | Jun 9, 2026 |
| 10-Q | Quarterly report | May 13, 2026 | Mar 31, 2026 |
| 8-K |
Current report
Results of operations
|
May 13, 2026 | May 13, 2026 |
All 134 Upstream Bio, Inc. SEC filings
Source: SEC EDGAR filings. This is company-reported data, not investment advice.