Synlogic, Inc. SYBX

FY2025 · ended Dec 31, 2025 · Revenue $0, -100.0% YoY · Filed Mar 12, 2026

Synlogic, Inc. (SYBX) files with the SEC under industry code 2834, Pharmaceutical Preparations. In fiscal 2025, which ended Dec 31, 2025, it reported revenue of $0 and a net loss of $1.0 million. Free cash flow was -$4.4 million.

Revenue (TTM)
$0
Net income (TTM)
$-655,000
+37.2% vs year-ago TTM
Operating cash flow (TTM)
$-3.84M
-19.5% vs year-ago TTM
Free cash flow
$-4.36M
+86.2% vs prior year
EPS (TTM)
$-0.05
+37.7% vs year-ago TTM
Dividend per share
None
Shares outstanding
11.70M
+0.0% vs prior year
Net cash
$18.86M
FY 2024
Operating margin
-511875.0%
FY 2024

Company profile

Industry
Pharmaceutical Preparations (SIC 2834)
Listed as
SYBX (OTC)
Fiscal year ends
December 31
Incorporated in
DE
Headquarters
Winchester, MA
SEC filer status
Non-accelerated filer, Smaller reporting company
SEC CIK
1527599
Former names
Mirna Therapeutics, Inc. (until Aug 25, 2017)

Other Pharmaceutical Preparations companies

Key figures

Fiscal-year totals from the annual reports. Balance sheet lines are as of each year end.

Line
FY 2025
Dec 31, 2025
FY 2024
Dec 31, 2024
FY 2023
Dec 31, 2023
FY 2022
Dec 31, 2022
FY 2021
Dec 31, 2021
Revenue
$0
$8,000
$3.4M
$1.2M
$1.8M
Operating income
-$4.0M
-$41.0M
-$55.2M
-$67.4M
-$60.8M
Net income
-$1.0M
-$23.4M
-$61.3M
-$66.1M
-$60.6M
Diluted EPS
-$0.08
-$1.92
-$9.42
-$13.83
—
Operating cash flow
-$4.4M
-$31.7M
-$51.6M
-$56.9M
-$52.2M
Free cash flow
-$4.4M
-$31.7M
-$51.8M
-$57.6M
-$52.9M
Total assets
$15.4M
$19.8M
$75.5M
$110.9M
$174.7M
Stockholders' equity
$11.9M
$12.8M
$32.8M
$82.6M
$147.3M
Cash and investments
$14.7M
$18.9M
$47.7M
$77.6M
$136.6M
Total debt
—
$0
$17.3M
$20.3M
$20.6M

Recent SEC filings

Recent SEC filings
Form Description Filed Period
10-Q Quarterly report Aug 11, 2026 Jun 30, 2026
8-K Current report
Material agreement, Change to shareholder rights, Change in control, Regulation FD disclosure
Jul 29, 2026 Jul 27, 2026
10-Q Quarterly report May 14, 2026 Mar 31, 2026
10-K/A Amended annual report Apr 30, 2026 Dec 31, 2025
10-K Annual report Mar 12, 2026 Dec 31, 2025
8-K/A Amended current report
Listing notice, Other events
Jan 29, 2026 Jan 16, 2026

Source: SEC EDGAR filings. This is company-reported data, not investment advice.