In fiscal 2025, which ended Dec 31, 2025, Sutro Biopharma, Inc. reported revenue of $102.5 million, up 65.2% from the year before. It recorded a net loss of $191.1 million. The operating loss came to $158.4 million, an operating margin of -154.5%. Diluted earnings per share were -$22.49. Over the twelve months ended Jun 30, 2026, revenue was $45.7 million and the net loss was $180.6 million. Across the 8 fiscal years shown, revenue grew from $38.4 million in fiscal 2018 to $102.5 million in fiscal 2025, about 15.0% a year.
USD in millions, except per-share amounts and margins. The percent under a figure is the change from the year before.
| Line |
FY 2026
Jun 30, 2026
|
FY 2025
Dec 31, 2025
|
FY 2024
Dec 31, 2024
|
FY 2023
Dec 31, 2023
|
FY 2022
Dec 31, 2022
|
FY 2021
Dec 31, 2021
|
FY 2020
Dec 31, 2020
|
FY 2019
Dec 31, 2019
|
FY 2018
Dec 31, 2018
|
|---|---|---|---|---|---|---|---|---|---|
| Revenue |
46
-56.3%
|
102
+65.2%
|
62
-59.6%
|
154
+126.8%
|
68
+9.5%
|
62
+44.8%
|
43
-0.0%
|
43
+11.2%
|
38
|
| Research and development |
145
-35.1%
|
166
-34.0%
|
252
+39.7%
|
180
+31.5%
|
137
+31.4%
|
104
+35.7%
|
77
+17.3%
|
66
+20.9%
|
54
|
| Selling, general and administrative |
33
-30.1%
|
41
-15.3%
|
48
-22.6%
|
63
+5.1%
|
60
+6.3%
|
56
+52.1%
|
37
+13.0%
|
33
+52.4%
|
21
|
| Restructuring and impairment |
—
|
13
|
—
|
—
|
—
|
—
|
—
|
—
|
—
|
| Operating income |
-146
+28.8%
|
-158
+33.6%
|
-238
-167.1%
|
-89
+30.8%
|
-129
-30.9%
|
-99
-38.7%
|
-71
-28.1%
|
-55
-49.0%
|
-37
|
| Pretax income |
-181
+12.4%
|
-191
+15.1%
|
-225
-154.1%
|
-89
+24.1%
|
-117
|
—
|
—
|
—
|
—
|
| Income tax |
-0
-104.1%
|
-0
-103.9%
|
2
-87.0%
|
18
+627.7%
|
2
|
0
-100.0%
|
0
|
0
|
0
|
| Net income |
-181
+13.4%
|
-191
+16.0%
|
-227
-113.0%
|
-107
+10.4%
|
-119
-12.9%
|
-106
-228.5%
|
-32
+73.0%
|
-119
-237.5%
|
-35
|
| Basic EPS |
-15.52
-274.9%
|
-22.49
+23.5%
|
-29.40
-1551.7%
|
-1.78
+24.3%
|
-2.35
|
—
|
—
|
—
|
—
|
| Diluted EPS |
-15.52
-274.9%
|
-22.49
+23.5%
|
-29.40
-1551.7%
|
-1.78
+24.3%
|
-2.35
|
—
|
—
|
—
|
—
|
| Weighted average shares, basic |
12
+149.5%
|
8
+9.8%
|
8
-87.1%
|
60
+18.6%
|
51
|
—
|
—
|
—
|
—
|
| Weighted average shares, diluted |
12
+149.5%
|
8
+9.8%
|
8
-87.1%
|
60
+18.6%
|
51
|
—
|
—
|
—
|
—
|
| Other measures | |||||||||
| Depreciation and amortization |
6
-18.8%
|
7
+1.5%
|
7
+5.9%
|
7
+19.8%
|
6
+17.5%
|
5
+12.7%
|
4
-10.0%
|
5
+5.2%
|
5
|
| EBITDA |
-140
+29.1%
|
-151
+34.7%
|
-231
-180.4%
|
-82
+33.1%
|
-123
-31.6%
|
-94
-40.3%
|
-67
-31.7%
|
-51
-55.1%
|
-33
|
| Interest coverage |
—
|
—
|
—
|
—
|
—
|
—
|
—
|
—
|
-22.93x
|
| Margins | |||||||||
| Operating margin |
-319.57%
|
-154.53%
|
-384.34%
|
-58.07%
|
-190.26%
|
-159.22%
|
-166.32%
|
-129.79%
|
-96.89%
|
| Pretax margin |
-395.46%
|
-186.55%
|
-362.81%
|
-57.63%
|
-172.20%
|
—
|
—
|
—
|
—
|
| Profit margin |
-395.25%
|
-186.45%
|
-366.62%
|
-69.47%
|
-175.89%
|
-170.55%
|
-75.20%
|
-278.93%
|
-91.93%
|
| EBITDA margin |
-306.31%
|
-147.38%
|
-372.70%
|
-53.64%
|
-181.86%
|
-151.39%
|
-156.27%
|
-118.61%
|
-85.07%
|
How these figures are calculated
Annual columns are full-year amounts from the annual report (Form 10-K, 20-F, or 40-F). If a company restates a year, the latest filed number is shown. USD in millions, except per-share amounts and margins. Weighted average shares are in millions. Interest expense and finance costs are positive costs. A negative amount on a gain (loss) or income (expense) line is a loss or an expense. EBITDA is operating income plus depreciation and amortization. Interest coverage is operating income divided by interest expense. The first column is the trailing twelve months through the latest quarter. More on our methodology.
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Company profile
- Industry
- Biological Products, (No Diagnostic Substances) (SIC 2836)
- Listed as
- STRO (Nasdaq)
- Fiscal year ends
- December 31
- Headquarters
- South San Francisco, CA
- SEC filer status
- Non-accelerated filer, Smaller reporting company
- SEC CIK
- 1382101
- Former names
- SUTRO BIOPHARMA INC (until Nov 8, 2018); Fundamental Applied Biology Inc (until Oct 24, 2007)
Other Biological Products, (No Diagnostic Substances) companies
- Amgen Inc AMGN
- Gilead Sciences, Inc. GILD
- Moderna, Inc. MRNA
- Argenx SE ARGX
- Revolution Medicines, Inc. RVMD
- Biogen Inc. BIIB
- BioNTech SE BNTX
- Exelixis, Inc. EXEL
All 182 Biological Products, (No Diagnostic Substances) companies
Source: SEC EDGAR filings. This is company-reported data, not investment advice.