Spruce Biosciences, Inc. SEC filings SPRB
Spruce Biosciences, Inc. has 366 filings in SEC EDGAR's recent list, going back to Feb 28, 2020. Its latest annual report, Form ARS, was filed on Apr 9, 2026 for the period ended Dec 31, 2025. The latest quarterly report (Form 10-Q) was filed on Aug 12, 2026, covering the quarter ended Jun 30, 2026. The most recent current report (Form 8-K) was filed on Aug 12, 2026 (results of operations). The company's fiscal year ends on December 31.
| Form | Description | Filed | Period |
|---|---|---|---|
| SCHEDULE 13G | Ownership over 5% (passive) | Aug 14, 2026 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | Aug 14, 2026 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | Aug 14, 2026 | — |
| SCHEDULE 13G | Ownership over 5% (passive) | Aug 14, 2026 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | Aug 4, 2026 | — |
| SCHEDULE 13G | Ownership over 5% (passive) | Jul 30, 2026 | — |
| 4 | Insider transaction | Jul 29, 2026 | Jul 27, 2026 |
| 3 | Initial insider ownership | Jul 29, 2026 | Jul 27, 2026 |
| SCHEDULE 13G | Ownership over 5% (passive) | Jul 27, 2026 | — |
| 4 | Insider transaction | Jul 9, 2026 | Jun 30, 2026 |
| 4 | Insider transaction | May 26, 2026 | May 21, 2026 |
| 4 | Insider transaction | May 26, 2026 | May 21, 2026 |
| 4 | Insider transaction | May 26, 2026 | May 21, 2026 |
| 4 | Insider transaction | May 26, 2026 | May 21, 2026 |
| 4 | Insider transaction | May 26, 2026 | May 21, 2026 |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | May 15, 2026 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | May 15, 2026 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | May 15, 2026 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | May 15, 2026 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | May 7, 2026 | — |
| SCHEDULE 13G | Ownership over 5% (passive) | Apr 28, 2026 | — |
| 4 | Insider transaction | Mar 9, 2026 | Mar 9, 2026 |
| 3 | Initial insider ownership | Mar 9, 2026 | Mar 9, 2026 |
| SCHEDULE 13G | Ownership over 5% (passive) | Feb 24, 2026 | — |
| SCHEDULE 13D/A | Amended ownership over 5% (active) | Feb 18, 2026 | — |
| SCHEDULE 13G | Ownership over 5% (passive) | Feb 17, 2026 | — |
| SCHEDULE 13G | Ownership over 5% (passive) | Feb 17, 2026 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | Feb 17, 2026 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | Feb 17, 2026 | — |
| SCHEDULE 13G | Ownership over 5% (passive) | Feb 10, 2026 | — |
| 4 | Insider transaction | Jan 21, 2026 | Dec 11, 2025 |
| 4 | Insider transaction | Jan 5, 2026 | Dec 31, 2025 |
| 4 | Insider transaction | Dec 17, 2025 | Dec 15, 2025 |
| 4 | Insider transaction | Dec 17, 2025 | Dec 11, 2025 |
| 4 | Insider transaction | Dec 15, 2025 | Dec 11, 2025 |
| 4 | Insider transaction | Dec 15, 2025 | Dec 11, 2025 |
| 4 | Insider transaction | Dec 15, 2025 | Dec 11, 2025 |
| 4 | Insider transaction | Dec 15, 2025 | Dec 11, 2025 |
| 4 | Insider transaction | Dec 15, 2025 | Dec 11, 2025 |
| 4 | Insider transaction | Dec 15, 2025 | Dec 11, 2025 |
| 4 | Insider transaction | Dec 15, 2025 | Dec 11, 2025 |
| 3 | Initial insider ownership | Dec 15, 2025 | Dec 11, 2025 |
| 4 | Insider transaction | Dec 12, 2025 | Dec 10, 2025 |
| 4 | Insider transaction | Dec 12, 2025 | Dec 10, 2025 |
| SCHEDULE 13G | Ownership over 5% (passive) | Nov 24, 2025 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | Nov 7, 2025 | — |
| 4 | Insider transaction | Oct 22, 2025 | Oct 20, 2025 |
| 4 | Insider transaction | Oct 22, 2025 | Oct 20, 2025 |
| SCHEDULE 13G | Ownership over 5% (passive) | Oct 16, 2025 | — |
| 4 | Insider transaction | Oct 15, 2025 | Oct 6, 2025 |
| 3 | Initial insider ownership | Oct 15, 2025 | Oct 6, 2025 |
| SCHEDULE 13G | Ownership over 5% (passive) | Oct 15, 2025 | — |
| SCHEDULE 13D/A | Amended ownership over 5% (active) | Oct 9, 2025 | — |
| 4 | Insider transaction | Oct 8, 2025 | Oct 6, 2025 |
| 3 | Initial insider ownership | Oct 8, 2025 | Oct 6, 2025 |
| SCHEDULE 13G | Ownership over 5% (passive) | Oct 8, 2025 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | Aug 13, 2025 | — |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | Aug 13, 2025 | — |
| 4 | Insider transaction | Jul 24, 2025 | Jul 22, 2025 |
| 4 | Insider transaction | Jul 24, 2025 | Jul 22, 2025 |
| 4 | Insider transaction | Jul 24, 2025 | Jul 22, 2025 |
| 4 | Insider transaction | Jul 24, 2025 | Jul 22, 2025 |
| 4 | Insider transaction | Jul 24, 2025 | Jul 22, 2025 |
| 4 | Insider transaction | Jul 24, 2025 | Jul 23, 2025 |
| 4 | Insider transaction | Jul 24, 2025 | Jul 22, 2025 |
| SCHEDULE 13G/A | Amended ownership over 5% (passive) | Feb 13, 2025 | — |
| SCHEDULE 13D/A | Amended ownership over 5% (active) | Jan 10, 2025 | — |
| 4 | Insider transaction | Dec 20, 2024 | Dec 10, 2024 |
| 4 | Insider transaction | Dec 20, 2024 | Dec 10, 2024 |
| 4 | Insider transaction | Dec 20, 2024 | Dec 10, 2024 |
| SC 13G/A | Amended ownership over 5% (passive) | Nov 14, 2024 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Nov 14, 2024 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Nov 12, 2024 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Oct 23, 2024 | — |
| 4 | Insider transaction | May 24, 2024 | May 22, 2024 |
| 4 | Insider transaction | May 24, 2024 | May 22, 2024 |
| 4 | Insider transaction | May 24, 2024 | May 22, 2024 |
| 4 | Insider transaction | May 24, 2024 | May 22, 2024 |
| 4 | Insider transaction | May 24, 2024 | May 22, 2024 |
| 4 | Insider transaction | May 24, 2024 | May 22, 2024 |
| 4 | Insider transaction | May 24, 2024 | May 22, 2024 |
| SC 13G/A | Amended ownership over 5% (passive) | Apr 25, 2024 | — |
| SC 13D/A | Amended ownership over 5% (active) | Mar 28, 2024 | — |
| SC 13G | Ownership over 5% (passive) | Mar 28, 2024 | — |
| SC 13D/A | Amended ownership over 5% (active) | Mar 25, 2024 | — |
| 4 | Insider transaction | Mar 25, 2024 | Mar 21, 2024 |
| SC 13D/A | Amended ownership over 5% (active) | Mar 20, 2024 | — |
| 4 | Insider transaction | Mar 20, 2024 | Mar 18, 2024 |
| 144 | Notice of proposed sale | Mar 18, 2024 | — |
| SC 13D/A | Amended ownership over 5% (active) | Mar 18, 2024 | — |
| 4 | Insider transaction | Mar 18, 2024 | Mar 14, 2024 |
| 4 | Insider transaction | Mar 18, 2024 | Mar 14, 2024 |
| 4 | Insider transaction | Mar 18, 2024 | Mar 14, 2024 |
| 4 | Insider transaction | Mar 18, 2024 | Mar 14, 2024 |
| 144 | Notice of proposed sale | Mar 14, 2024 | — |
| SC 13D/A | Amended ownership over 5% (active) | Mar 7, 2024 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 14, 2024 | — |
| SC 13G | Ownership over 5% (passive) | Feb 14, 2024 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 14, 2024 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 6, 2024 | — |
| SC 13G | Ownership over 5% (passive) | Jan 30, 2024 | — |
| 4 | Insider transaction | Jan 3, 2024 | Dec 29, 2023 |
| 4 | Insider transaction | Jan 3, 2024 | Dec 29, 2023 |
| 4 | Insider transaction | Dec 18, 2023 | Dec 14, 2023 |
| 4 | Insider transaction | Dec 18, 2023 | Dec 14, 2023 |
| 4 | Insider transaction | Dec 18, 2023 | Dec 14, 2023 |
| 4 | Insider transaction | Nov 28, 2023 | Nov 26, 2023 |
| 4 | Insider transaction | Nov 13, 2023 | Nov 8, 2023 |
| 4 | Insider transaction | Jul 5, 2023 | Jun 30, 2023 |
| 4 | Insider transaction | Jul 5, 2023 | Jun 30, 2023 |
| 4 | Insider transaction | Jul 5, 2023 | Jun 30, 2023 |
| SC 13D/A | Amended ownership over 5% (active) | May 30, 2023 | — |
| 4 | Insider transaction | May 26, 2023 | May 25, 2023 |
| 4 | Insider transaction | May 26, 2023 | May 25, 2023 |
| 4 | Insider transaction | May 26, 2023 | May 25, 2023 |
| 4 | Insider transaction | May 26, 2023 | May 25, 2023 |
| 4 | Insider transaction | May 26, 2023 | May 25, 2023 |
| 4 | Insider transaction | May 26, 2023 | May 25, 2023 |
| 4 | Insider transaction | May 26, 2023 | May 25, 2023 |
| 4 | Insider transaction | May 26, 2023 | May 25, 2023 |
| 3 | Initial insider ownership | May 26, 2023 | May 25, 2023 |
| 4 | Insider transaction | May 16, 2023 | Feb 16, 2023 |
| SC 13G | Ownership over 5% (passive) | Feb 27, 2023 | — |
| SC 13D/A | Amended ownership over 5% (active) | Feb 23, 2023 | — |
| SC 13D/A | Amended ownership over 5% (active) | Feb 21, 2023 | — |
| 4 | Insider transaction | Feb 21, 2023 | Feb 16, 2023 |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 14, 2023 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 14, 2023 | — |
| SC 13D/A | Amended ownership over 5% (active) | Feb 13, 2023 | — |
| 4 | Insider transaction | Jan 5, 2023 | Dec 30, 2022 |
| 4 | Insider transaction | Jan 5, 2023 | Dec 30, 2022 |
| 4 | Insider transaction | Jan 5, 2023 | Jan 3, 2023 |
| 4 | Insider transaction | Dec 7, 2022 | Dec 5, 2022 |
| 4 | Insider transaction | Dec 7, 2022 | Dec 5, 2022 |
| 4 | Insider transaction | Dec 7, 2022 | Dec 5, 2022 |
| SC 13D/A | Amended ownership over 5% (active) | Sep 30, 2022 | — |
| SC 13D/A | Amended ownership over 5% (active) | Aug 11, 2022 | — |
| 4/A | Form 4/a submission | Jul 5, 2022 | Dec 31, 2021 |
| 4 | Insider transaction | Jul 5, 2022 | Jun 30, 2022 |
| 4 | Insider transaction | May 27, 2022 | May 25, 2022 |
| 4 | Insider transaction | May 27, 2022 | May 25, 2022 |
| 4 | Insider transaction | May 27, 2022 | May 25, 2022 |
| 4 | Insider transaction | May 27, 2022 | May 25, 2022 |
| 4 | Insider transaction | May 27, 2022 | May 25, 2022 |
| 4 | Insider transaction | May 27, 2022 | May 25, 2022 |
| 4 | Insider transaction | May 27, 2022 | May 25, 2022 |
| 4 | Insider transaction | May 27, 2022 | May 25, 2022 |
| 4 | Insider transaction | Apr 1, 2022 | Apr 1, 2022 |
| 3 | Initial insider ownership | Apr 1, 2022 | Mar 28, 2022 |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 15, 2022 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 14, 2022 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 11, 2022 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 9, 2022 | — |
| 4 | Insider transaction | Jan 10, 2022 | Jan 3, 2022 |
| 3 | Initial insider ownership | Jan 10, 2022 | Jan 1, 2022 |
| 4 | Insider transaction | Jan 5, 2022 | Dec 31, 2021 |
| 4 | Insider transaction | Dec 20, 2021 | Dec 16, 2021 |
| 4 | Insider transaction | Dec 20, 2021 | Dec 16, 2021 |
| 4 | Insider transaction | Dec 20, 2021 | Dec 16, 2021 |
| SC 13D/A | Amended ownership over 5% (active) | Nov 22, 2021 | — |
| 4 | Insider transaction | Jul 6, 2021 | Jun 30, 2021 |
| 4 | Insider transaction | Jul 6, 2021 | Jun 30, 2021 |
| 4 | Insider transaction | Jun 25, 2021 | Jun 23, 2021 |
| 3 | Initial insider ownership | Jun 25, 2021 | Jun 23, 2021 |
| 4 | Insider transaction | May 21, 2021 | May 20, 2021 |
| 4 | Insider transaction | May 21, 2021 | May 20, 2021 |
| 4 | Insider transaction | May 21, 2021 | May 20, 2021 |
| 4 | Insider transaction | May 21, 2021 | May 20, 2021 |
| 4 | Insider transaction | May 21, 2021 | May 20, 2021 |
| 4 | Insider transaction | May 21, 2021 | May 20, 2021 |
| SC 13D/A | Amended ownership over 5% (active) | May 21, 2021 | — |
| 4 | Insider transaction | May 21, 2021 | May 19, 2021 |
| SC 13G | Ownership over 5% (passive) | May 17, 2021 | — |
| 4 | Insider transaction | May 4, 2021 | Apr 30, 2021 |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 16, 2021 | — |
| SC 13G/A | Amended ownership over 5% (passive) | Feb 16, 2021 | — |
| SC 13G | Ownership over 5% (passive) | Feb 12, 2021 | — |
| SC 13G | Ownership over 5% (passive) | Feb 12, 2021 | — |
| SC 13G | Ownership over 5% (passive) | Feb 8, 2021 | — |
| 4 | Insider transaction | Jan 29, 2021 | Jan 28, 2021 |
| 4 | Insider transaction | Jan 29, 2021 | Jan 28, 2021 |
| 4 | Insider transaction | Jan 29, 2021 | Jan 28, 2021 |
| SC 13D | Ownership over 5% (active) | Dec 18, 2020 | — |
| SC 13G | Ownership over 5% (passive) | Oct 26, 2020 | — |
| SC 13D | Ownership over 5% (active) | Oct 23, 2020 | — |
| SC 13G | Ownership over 5% (passive) | Oct 19, 2020 | — |
| 4 | Insider transaction | Oct 16, 2020 | Oct 14, 2020 |
| SC 13D | Ownership over 5% (active) | Oct 16, 2020 | — |
| SC 13D | Ownership over 5% (active) | Oct 16, 2020 | — |
| 4 | Insider transaction | Oct 16, 2020 | Oct 14, 2020 |
| 4 | Insider transaction | Oct 16, 2020 | Oct 14, 2020 |
| 4 | Insider transaction | Oct 16, 2020 | Oct 14, 2020 |
| 4 | Insider transaction | Oct 16, 2020 | Oct 14, 2020 |
| 4 | Insider transaction | Oct 16, 2020 | Oct 14, 2020 |
| 4 | Insider transaction | Oct 16, 2020 | Oct 14, 2020 |
| 4 | Insider transaction | Oct 16, 2020 | Oct 14, 2020 |
| 3 | Initial insider ownership | Oct 8, 2020 | Oct 8, 2020 |
| 3 | Initial insider ownership | Oct 8, 2020 | Oct 8, 2020 |
| 3 | Initial insider ownership | Oct 8, 2020 | Oct 8, 2020 |
| 3 | Initial insider ownership | Oct 8, 2020 | Oct 8, 2020 |
Showing 200 filings, the most recent 200. Main filings leave out insider and ownership forms such as Form 4; choose a type above to see them. Each form opens on SEC.gov. Older filings are on SEC EDGAR.
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Company profile
- Industry
- Pharmaceutical Preparations (SIC 2834)
- Listed as
- SPRB (Nasdaq)
- Fiscal year ends
- December 31
- Incorporated in
- DE
- Headquarters
- South San Francisco, CA
- SEC filer status
- Non-accelerated filer, Smaller reporting company
- SEC CIK
- 1683553
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Source: SEC EDGAR filings. This is company-reported data, not investment advice.