In fiscal 2025, which ended Dec 31, 2025, Q32 Bio Inc. reported revenue of $53.7 million. Net income was $29.8 million, a profit margin of 55.5%. Operating income came to $16.9 million, an operating margin of 31.5%. Diluted earnings per share were $2.42. Across the 7 fiscal years shown, revenue grew from $3.7 million in fiscal 2018 to $53.7 million in fiscal 2025, about 56.3% a year.
USD in millions, except per-share amounts and margins. The percent under a figure is the change from the year before.
| Line |
FY 2025
Dec 31, 2025
|
FY 2024
Dec 31, 2024
|
FY 2023
Dec 31, 2023
|
FY 2022
Dec 31, 2022
|
FY 2021
Dec 31, 2021
|
FY 2020
Dec 31, 2020
|
FY 2019
Dec 31, 2019
|
FY 2018
Dec 31, 2018
|
|---|---|---|---|---|---|---|---|---|
| Revenue |
54
|
0
-100.0%
|
1
-64.0%
|
3
-90.6%
|
34
+1157.3%
|
3
+62.2%
|
2
-54.8%
|
4
|
| Research and development |
19
-60.2%
|
48
+51.7%
|
32
-67.7%
|
98
+5.7%
|
93
-7.3%
|
100
+12.3%
|
89
+86.4%
|
48
|
| Selling, general and administrative |
18
-1.6%
|
18
+81.9%
|
10
-74.1%
|
38
+3.5%
|
37
+13.1%
|
33
+46.7%
|
22
+28.4%
|
17
|
| Other operating income (expense) |
0
-73.3%
|
2
|
—
|
—
|
—
|
—
|
—
|
—
|
| Operating income |
17
+125.6%
|
-66
-37.0%
|
-48
+63.8%
|
-133
-38.9%
|
-96
+26.3%
|
-130
-18.5%
|
-110
-83.5%
|
-60
|
| Other income (expense) |
13
-35.5%
|
20
|
—
|
—
|
—
|
—
|
—
|
—
|
| Pretax income |
30
+164.7%
|
-46
+47.1%
|
-87
-7368.8%
|
1
|
—
|
—
|
—
|
—
|
| Income tax |
0
-100.0%
|
0
-93.4%
|
0
-55.5%
|
1
|
0
|
0
|
0
|
0
|
| Net income |
30
+162.5%
|
-48
+11.2%
|
-54
-973.8%
|
-5
+94.8%
|
-96
+25.6%
|
-129
-23.8%
|
-104
-87.0%
|
-56
|
| Net income to common |
0
+162.5%
|
-0
|
—
|
—
|
—
|
—
|
—
|
—
|
| Basic EPS |
2.42
+147.3%
|
-5.12
+96.7%
|
-153.96
-170966.7%
|
-0.09
|
—
|
—
|
—
|
—
|
| Diluted EPS |
2.42
+136.8%
|
-6.58
+95.7%
|
-153.96
-170966.7%
|
-0.09
|
—
|
—
|
—
|
—
|
| Weighted average shares, basic |
12
+32.0%
|
9
+2570.3%
|
0
-99.4%
|
57
|
—
|
—
|
—
|
—
|
| Weighted average shares, diluted |
12
+27.5%
|
10
+2666.8%
|
0
-99.4%
|
57
|
—
|
—
|
—
|
—
|
| Other measures | ||||||||
| Depreciation and amortization |
0
-19.7%
|
0
-2.4%
|
0
-61.4%
|
1
-84.5%
|
8
+4.9%
|
8
+26.1%
|
6
+390.1%
|
1
|
| EBITDA |
17
+126.4%
|
-66
-37.4%
|
-48
+63.8%
|
-132
-50.7%
|
-88
+28.4%
|
-122
-18.0%
|
-104
-76.7%
|
-59
|
| Margins | ||||||||
| Operating margin |
31.45%
|
—
|
-4,174.31%
|
-4,154.64%
|
-282.44%
|
-4,820.98%
|
-6,599.22%
|
-1,626.66%
|
| Pretax margin |
55.49%
|
—
|
-7,532.87%
|
37.34%
|
—
|
—
|
—
|
—
|
| Profit margin |
55.49%
|
—
|
-4,649.05%
|
-156.02%
|
-281.90%
|
-4,762.92%
|
-6,237.45%
|
-1,508.60%
|
| EBITDA margin |
32.18%
|
—
|
-4,131.14%
|
-4,114.34%
|
-257.86%
|
-4,526.20%
|
-6,219.99%
|
-1,591.67%
|
| Effective tax rate |
0.00%
|
—
|
—
|
59.68%
|
—
|
—
|
—
|
—
|
How these figures are calculated
Annual columns are full-year amounts from the annual report (Form 10-K, 20-F, or 40-F). If a company restates a year, the latest filed number is shown. USD in millions, except per-share amounts and margins. Weighted average shares are in millions. Interest expense and finance costs are positive costs. A negative amount on a gain (loss) or income (expense) line is a loss or an expense. EBITDA is operating income plus depreciation and amortization. Interest coverage is operating income divided by interest expense. More on our methodology.
New to this? Read How to Read an Income Statement, With a Real Example.
Company profile
- Industry
- Pharmaceutical Preparations (SIC 2834)
- Listed as
- QTTB (Nasdaq)
- Fiscal year ends
- December 31
- Incorporated in
- DE
- Headquarters
- Waltham, MA
- SEC filer status
- Non-accelerated filer, Smaller reporting company
- SEC CIK
- 1661998
- Former names
- Q32 Bio Inc. (until Nov 4, 2026); Homology Medicines, Inc. (until Mar 22, 2024)
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Source: SEC EDGAR filings. This is company-reported data, not investment advice.