OPKO Health, Inc. revenue by segment OPK

Annual Quarterly

OPKO Health, Inc. splits its revenue into 7 lines in its filings. The largest line in fiscal 2025, which ended Dec 31, 2025 was Services at $370.3 million, 61% of the total.

USD in millions. The percent under a figure is the change from the year before.

Line	FY 2026 Sep 30, 2026	FY 2025 Dec 31, 2025	FY 2024 Dec 31, 2024	FY 2023 Dec 31, 2023	FY 2022 Dec 31, 2022	FY 2021 Dec 31, 2021	FY 2020 Dec 31, 2020	FY 2019 Dec 31, 2019	FY 2018 Dec 31, 2018	FY 2017 Dec 31, 2017	FY 2016 Dec 31, 2016
Revenue	654	607	713	863	1,004	1,775	1,435	902	990	1,068	1,222
Client Payers	—	—	—	—	—	843 +32.3% share 47.5%	638 +302.2% share 44.4%	159 +7.1% share 17.6%	148 +17.3% share 15.0%	126 share 11.8%	—
Health Insurers	—	—	—	—	—	520 +7.6% share 29.3%	484 share 33.7%	—	493 -0.4% share 49.8%	495 share 46.4%	—
Services	—	370 -23.0% share 61.0%	481 -6.7% share 67.4%	515 -31.8% share 59.7%	756 share 75.2%	—	—	—	—	—	—
Government Payers	—	—	—	—	—	222 +146.1% share 12.5%	90 -22.0% share 6.3%	116 -23.3% share 12.8%	151 +7.6% share 15.2%	140 share 13.1%	—
Product	—	157 +1.2% share 25.9%	155 -7.4% share 21.8%	168 +17.3% share 19.4%	143 +0.8% share 14.2%	142 +18.2% share 8.0%	120 +6.9% share 8.4%	112 share 12.4%	—	108 share 10.1%	—
License And Service	—	80 +3.0% share 13.1%	77 -57.2% share 10.8%	181 +70.9% share 20.9%	106 +309.1% share 10.5%	26 -51.4% share 1.5%	53 -27.4% share 3.7%	73 +4.9% share 8.1%	70 -7.5% share 7.1%	76 share 7.1%	—
Patients	—	—	—	—	—	21 -58.1% share 1.2%	51 +143.5% share 3.5%	21 -2.4% share 2.3%	21 +1.4% share 2.2%	21 share 2.0%	—

How these figures are calculated

Annual columns are full-year amounts from the annual report (Form 10-K, 20-F, or 40-F). If a company restates a year, the latest filed number is shown. USD in millions. Each group is a separate split of total revenue, so the groups are not added together. Share of revenue is that line divided by total revenue. The first column adds the latest year-to-date segment amount to the last fiscal year and subtracts the year-ago year-to-date amount. More on our methodology.

Company profile

Industry: Pharmaceutical Preparations (SIC 2834)
Listed as: OPK (Nasdaq)
Fiscal year ends: December 31
Incorporated in: DE
Headquarters: Miami, FL
SEC filer status: Accelerated filer
SEC CIK: 944809
Former names: EXEGENICS INC (until Jun 13, 2007); eXegenics Inc (until Jun 13, 2007); CYTOCLONAL PHARMACEUTICS INC /DE (until Jun 4, 2001)

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Source: SEC EDGAR filings. This is company-reported data, not investment advice.