Q2 FY2026 · ended Jun 30, 2026 · Revenue $267.95M, -40.7% YoY · Filed Jul 29, 2026
Ionis Pharmaceuticals, Inc. (IONS) files with the SEC under industry code 2834, Pharmaceutical Preparations. In Q2 of fiscal 2026, the quarter ended Jun 30, 2026, it reported revenue of $267.9 million and a net loss of $114.6 million. Free cash flow was $549.5 million. As of Jun 30, 2026 it held $2.7 billion in cash and investments and $262.5 million in total debt.
Revenue
$267.95M
-40.7% vs year-ago quarter
Net income
$-114.65M
-192.8% vs year-ago quarter
Operating cash flow
$565.53M
+273.7% vs year-ago quarter
Free cash flow
$549.45M
+295.2% vs year-ago quarter
EPS
$-0.69
-23.2% vs prior quarter
Dividend per share
None
Shares outstanding
166.18M
+4.3% vs year-ago quarter
Net cash
$2.44B
Q2 FY2026
Operating margin
-68.0%
TTM
Company profile
- Industry
- Pharmaceutical Preparations (SIC 2834)
- Listed as
- IONS (Nasdaq)
- Fiscal year ends
- December 31
- Incorporated in
- CA
- Headquarters
- Carlsbad, CA
- SEC filer status
- Large accelerated filer
- SEC CIK
- 874015
- Former names
- ISIS PHARMACEUTICALS INC (until Dec 18, 2015)
Other Pharmaceutical Preparations companies
- ELI LILLY & Co LLY
- Johnson & Johnson JNJ
- AbbVie Inc. ABBV
- Merck & Co., Inc. MRK
- Novartis AG NVS
- Astrazeneca PLC AZN
- Abbott Laboratories ABT
- Novo Nordisk A S NVO
Key figures
Fiscal-year totals from the annual reports; switch to Annual for the full-year view. Balance sheet lines are as of each year end.
| Line | Q2 FY2026 Jun 30, 2026 |
Q1 FY2026 Mar 31, 2026 |
Q4 FY2025 Dec 31, 2025 |
Q3 FY2025 Sep 30, 2025 |
Q2 FY2025 Jun 30, 2025 |
|---|---|---|---|---|---|
| Revenue | $267.9M | $246.1M | $203.3M | $156.7M | $452.0M |
| Operating income | -$102.3M | -$117.4M | -$214.5M | -$160.2M | $139.8M |
| Net income | -$114.6M | -$92.5M | -$229.4M | -$128.6M | $123.6M |
| Diluted EPS | -$0.69 | -$0.56 | -$1.41 | -$0.80 | — |
| Operating cash flow | $565.5M | -$792.8M | -$137.7M | -$131.4M | $151.3M |
| Free cash flow | $549.5M | -$814.6M | -$159.0M | -$136.7M | $139.0M |
| Total assets | $3.0B | $3.4B | $3.5B | $3.0B | $3.0B |
| Total liabilities | $2.6B | $3.0B | $3.0B | $2.4B | $2.4B |
| Stockholders' equity | $439.7M | $491.4M | $489.1M | $618.0M | $631.7M |
| Cash and investments | $2.7B | $2.5B | $3.5B | $2.9B | $3.0B |
| Total debt | $262.5M | $259.2M | $2.1B | $262.7M | $164.4M |
Recent SEC filings
| Form | Description | Filed | Period |
|---|---|---|---|
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Oct 23, 2026 | Oct 23, 2026 |
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Oct 21, 2026 | Oct 20, 2026 |
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Sep 23, 2026 | Sep 23, 2026 |
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Sep 4, 2026 | Sep 4, 2026 |
| 8-K |
Current report
Regulation FD disclosure, Other events
|
Sep 4, 2026 | Sep 3, 2026 |
| 10-Q | Quarterly report | Jul 29, 2026 | Jun 30, 2026 |
All 1005 Ionis Pharmaceuticals, Inc. SEC filings
Source: SEC EDGAR filings. This is company-reported data, not investment advice.