Crescent Biopharma, Inc. CBIO

FY2025 · ended Dec 31, 2025 · Revenue $10.84M, +108340.0% YoY · Filed Feb 26, 2026

Crescent Biopharma, Inc. (CBIO) files with the SEC under industry code 2834, Pharmaceutical Preparations. In fiscal 2025, which ended Dec 31, 2025, it reported revenue of $10.8 million and a net loss of $153.9 million. Free cash flow was -$72.5 million. As of Jun 30, 2026 it held $171.6 million in cash and investments and $1.4 million in total debt.

Revenue
$10.84M
+108340.0% vs prior year
Net income (TTM)
$-165.12M
Operating cash flow (TTM)
$-72.68M
-86.6% vs year-ago TTM
Free cash flow (TTM)
$-73.62M
-88.3% vs year-ago TTM
EPS
$-0.59
-1.7% vs prior year
Dividend per share
None
Shares outstanding
27.56M
-57.3% vs prior year
Net cash
$170.16M
as of Jun 30, 2026
Operating margin
-1407.5%
FY 2025

Company profile

Industry
Pharmaceutical Preparations (SIC 2834)
Listed as
CBIO (Nasdaq)
Fiscal year ends
December 31
Incorporated in
Cayman Islands
Headquarters
Waltham, MA
SEC filer status
Non-accelerated filer, Smaller reporting company
SEC CIK
1253689
Former names
GLYCOMIMETICS INC (until Jun 23, 2025)

Other Pharmaceutical Preparations companies

Key figures

Fiscal-year totals from the annual reports. Balance sheet lines are as of each year end.

Line
FY 2025
Dec 31, 2025
FY 2024
Dec 31, 2024
FY 2023
Dec 31, 2023
FY 2022
Dec 31, 2022
FY 2021
Dec 31, 2021
Revenue
$10.8M
—
$10,000
$75,000
$1.2M
Operating income
-$152.6M
-$40.0M
-$39.3M
-$47.4M
-$63.4M
Net income
-$153.9M
-$37.9M
-$36.9M
-$46.7M
-$63.4M
Diluted EPS
—
-$0.59
-$0.58
-$0.89
-$1.23
Operating cash flow
-$71.5M
-$31.1M
-$34.9M
-$46.5M
-$57.5M
Free cash flow
-$72.5M
-$31.1M
-$34.9M
-$46.5M
-$57.5M
Total assets
$240.3M
$35.6M
$45.3M
$51.8M
$94.3M
Total liabilities
$37.3M
$47.1M
$6.9M
$8.9M
$12.7M
Stockholders' equity
$203.0M
-$15.5M
$38.4M
$42.9M
$81.6M
Cash and investments
$213.2M
$34.8M
$41.8M
$47.9M
$90.3M
Total debt
$1.6M
$66,844
$808,402
$918,555
$1.9M

Recent SEC filings

Recent SEC filings
Form Description Filed Period
8-K Current report
Other events
Oct 15, 2026 Oct 15, 2026
10-Q Quarterly report Jul 30, 2026 Jun 30, 2026
8-K Current report
Results of operations
Jul 30, 2026 Jul 30, 2026
8-K Current report
Other events
Jul 15, 2026 Jul 14, 2026
8-K Current report
Results of operations
Jul 14, 2026 Jul 14, 2026
10-Q/A Amended quarterly report Jun 22, 2026 Mar 31, 2026

Source: SEC EDGAR filings. This is company-reported data, not investment advice.